Analysis and quantification of morphological and structural changes in cartilage; assessment of existing and derivation of new image-based scores for gradual cartilage loss

S. Zachow, Zuse Institute Berlin (ZIB)

Abstract: The aim of this project is to assess and to quantitatively analyse morphological and structural changes in cartilage with respect to different levels of exercise to support the hypothesis that cartilage competence is maintained through muscle strengthening. It is assumed that morphology and structure of cartilage and muscle as well as progression of osteoarthritis can be quantitatively assessed with medical imaging techniques. The proposed work program is focussed on monitoring and analysis of changes in cartilage volume, shape, and quality   based on different but combined medical imaging modalities and its relation to existing osteoarthritis scores.

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